rs661561, TNFAIP3

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
CUI: C1961099
Disease: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
0.010 GeneticVariation BEFREE The homozygous form (CC) of rs661561 was detected in all 10 cases with detectable T-ALL, while only 80% (24/30) of the healthy controls had this genotype. 24611736 2014
Graves Disease
CUI: C0018213
Disease: Graves Disease
0.010 GeneticVariation BEFREE The ATC haplotype (rs598493, rs661561 and rs610604) was associated with a decreased risk of GD. 24798189 2014
Autoimmune thyroid disease (AITD)
CUI: C3840565
Disease: Autoimmune thyroid disease (AITD)
0.010 GeneticVariation BEFREE Three single nucleotide polymorphisms (SNPs) in TNFAIP3 gene locus (rs598493, rs610604 and rs661561) were detected in a set of 667 patients with AITD and 301 controls in Han Chinese population using the Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometer (MALDI-TOF-MS) Platform. 24798189 2014