|
Cerebrovascular accident
|
|
0.010 |
GeneticVariation
|
BEFREE |
Subgroup analysis indicated that rs10435816 (additive model: OR=0.61, 95%CI, 0.41-0.89; recessive model: OR=0.56, 95%CI, 0.40-0.80), rs7025417 (additive model: OR=0.57, 95%CI, 0.39-0.83), rs11792633 (additive model: OR=0.66, 95%CI, 0.46-0.95; recessive model: OR=0.67, 95%CI, 0.49-0.93), and rs7044343 (additive model: OR=0.69, 95%CI, 0.48-0.97; recessive model: OR=0.67, 95%CI, 0.49-0.91) were associated with a decreased risk of large-artery atherosclerosis stroke after adjustment of confounding factors.
|
31660817 |
2019 |
|
Asthma
|
|
0.010 |
GeneticVariation
|
BEFREE |
No association was found between rs7044343 variant and asthma.
|
28985997 |
2018 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
When patients were divided into groups with and without type 2 diabetes mellitus (T2DM), the rs7044343 T allele was associated with a reduced risk of premature CAD in patients without (OR = 0.85, 95% CI: 0.73-0.99, Padd = 0.038) and with T2DM (OR = 0.61, 95% CI: 0.38-0.97, Pdom = 0.039; OR = 0.69, 95% CI: 0.49-0.97, Padd = 0.035).
|
28045954 |
2017 |
|
Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results suggest that the IL-33 rs7044343 T allele could be a susceptibility marker for premature CAD and central obesity.
|
28045954 |
2017 |
|
Alzheimer Disease, Late Onset
|
|
0.010 |
GeneticVariation
|
BEFREE |
Additionally, there was an apparent association between the IL-33 rs7044343 variant and LOAD ri</span>sk under four genetic models for overall population (heterozygous comparison model: OR =0.75, 95% CI =0.63-0.89; dominant model: OR =0.83, 95% CI =0.70-0.98; recessive model: OR =0.80, 95% CI =0.68-0.94; allelic model: OR =0.86, 95% CI =0.79-0.94) as well as Caucasian subgroup.
|
28919759 |
2017 |
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results suggest that the IL-33 rs7044343 T allele could be a susceptibility marker for premature CAD and central obesity.
|
28045954 |
2017 |
|
Premature coronary artery atherosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs7044343 Polymorphism of the Interleukin 33 Gene Is Associated with Decreased Risk of Developing Premature Coronary Artery Disease and Central Obesity, and Could Be Involved in Regulating the Production of IL-33.
|
28045954 |
2017 |
|
Drug abuse
|
|
0.010 |
GeneticVariation
|
BEFREE |
First, we show that a 2-SNP haplotype in the IL-33 gene (rs11792633 and rs7044343) moderated the link between women's history of childhood abuse and their history of recurrent MDD (rMDD), such that the link between childhood abuse and rMDD was stronger among women with fewer copies of the protective IL-33 CT haplotype.
|
27054346 |
2016 |
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, we found no strong evidence for the association of IL-33 rs7044343 polymorphism with SLE.
|
27603301 |
2016 |
|
Systemic Scleroderma
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, CC genotype of rs7044343 SNP was significantly higher in the SSc group compared to the HC group (P = 0.013, OR 1.75, 95 % CI 1.12-2.72).
|
26743213 |
2016 |
|
Behcet Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs7044343 and rs11792633 variants of IL-33 gene are associated with the decreased risk of BD in our cohort.
|
25119832 |
2015 |
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The CC genotype of rs7044343 in IL33 is associated with RA patients and downregulates IL-33 expression in RA.
|
24779919 |
2014 |
|
Alzheimer's Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Three intronic rs1157505, rs11792633, and rs7044343 single nucleotide polymorphisms (SNPs) within IL-33 have recently been reported to be associated with risk of AD in Caucasian populations.
|
20708824 |
2012 |