rs770572030, LIPG

N. diseases: 5
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE There was a significant difference between 584C/T polymorphism in the EL gene and CAD and HDL level. 31020688 2019
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE The endothelial lipase gene (584 C/T) T allele might be protective in association with coronary artery disease. 30150432 2018
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE To investigate the relationship between the common single nucleotide polymorphisms (SNPs) 584C/T (rs2000813) and -384A/C (rs3813082) in the LIPG gene and CAD, allele and genotype frequencies of the two SNPs were analysed in 287 Chinese patients with CAD and 367 controls by the high-resolution melting curve (HRM) method. 26124511 2015
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE The EL 584C/T gene polymorphism, therefore, was not associated with early-onset CAD or the severity of CAD in this Chinese Han population, suggesting that this variant is not always involved in the pathogenesis of early-onset CAD. 24634127 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE The associations between endothelial lipase 584C/T polymorphism and HDL-C level and coronary heart disease susceptibility: a meta-analysis. 24886585 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.060 GeneticVariation BEFREE The aim of the present study was to assess the influence of the endothelial lipase (EL) gene 584C/T variant, which results in a change at codon 111 of the EL gene from threonine to isoleucine, on the risk of coronary artery disease (CAD) in a Chinese population. 17986713 2008
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.030 GeneticVariation BEFREE Association of 584C/T polymorphism in endothelial lipase gene with risk of coronary artery disease. 31020688 2019
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.030 GeneticVariation BEFREE Association of 584C/T polymorphism in endothelial lipase gene with risk of coronary artery disease. 31020688 2019
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.030 GeneticVariation BEFREE The endothelial lipase gene (584 C/T) T allele might be protective in association with coronary artery disease. 30150432 2018
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.030 GeneticVariation BEFREE The endothelial lipase gene (584 C/T) T allele might be protective in association with coronary artery disease. 30150432 2018
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.030 GeneticVariation BEFREE We calculated the pooled ORs again after excluding Tang's study and found the association between EL 584C/T polymorphism and the risk of CHD was not significant for any genetic model. 24886585 2014
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.030 GeneticVariation BEFREE The associations between endothelial lipase 584C/T polymorphism and HDL-C level and coronary heart disease susceptibility: a meta-analysis. 24886585 2014
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.010 GeneticVariation BEFREE The c.584C>T EL polymorphism is associated with a higher risk of diabetic retinopathy that could be linked to modifications in HDL-cholesterol metabolism and blood pressure levels. 21145773 2011
Acute myocardial infarction
CUI: C0155626
Disease: Acute myocardial infarction
0.010 GeneticVariation BEFREE The 584C/T polymorphism of the EL gene was associated with AMI independently of HDL-C levels and thus may be involved in the pathogenesis of AMI. 17526978 2007