|
Liver carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
HULC rs7763881 AC/CC genotype was significantly associated with decreased HCC risk.
|
31009106 |
2019 |
|
Liver carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
The variant genotypes of rs7763881 in HULC may contribute to decreased susceptibility to HCC in HBV persistent carriers.
|
22493738 |
2012 |
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our study also demonstrated that other SNPs were correlated with overall cancer risk, namely, metastasis-associated lung adenocarcinoma transcript 1 (MALAT1, rs619586 A/G), HOXA distal transcript antisense RNA (HOTTIP, rs1859168 A/C), and highly up-regulated in liver cancer (HULC, rs7763881 A/C).
|
29802154 |
2018 |
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our study also demonstrated that other SNPs were correlated with overall cancer risk, namely, metastasis-associated lung adenocarcinoma transcript 1 (MALAT1, rs619586 A/G), HOXA distal transcript antisense RNA (HOTTIP, rs1859168 A/C), and highly up-regulated in liver cancer (HULC, rs7763881 A/C).
|
29802154 |
2018 |
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, rs6983267 and rs7763881 are potential genetic markers of CRC predisposition and correlate with serum CCAT2 and HULC, two novel potential non-invasive diagnostic biomarkers for CRC.
|
29176650 |
2017 |
|
SVEINSSON CHORIORETINAL ATROPHY
|
|
0.010 |
GeneticVariation
|
BEFREE |
Serum CCAT2 and HULC were upregulated in CRC and AP patients versus controls and discriminated these groups by ROC analysis. rs6983267 GG and rs7763881 AA patients demonstrated higher serum CCAT2 and HULC compared with GT/TT and AC, respectively. rs6983267 and serum HULC predicted CRC diagnosis among non-CRC groups (AP + controls) by multivariate analysis.
|
29176650 |
2017 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of rs6983267 at 8q24, HULC rs7763881 polymorphisms and serum lncRNAs CCAT2 and HULC with colorectal cancer in Egyptian patients.
|
29176650 |
2017 |
|
Adenomatous Polyps
|
|
0.010 |
GeneticVariation
|
BEFREE |
Studied SNPs were not associated with AP susceptibility. rs6983267 GG was associated with increased CRC risk, whereas rs7763881 AC was protective. rs7763881 and rs6983267 CT haplotype was protective.
|
29176650 |
2017 |
|
Esophageal Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Long noncoding RNAs POLR2E rs3787016 C/T and HULC rs7763881 A/C polymorphisms are associated with decreased risk of esophageal cancer.
|
25874495 |
2015 |
|
Esophageal carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Long noncoding RNAs POLR2E rs3787016 C/T and HULC rs7763881 A/C polymorphisms are associated with decreased risk of esophageal cancer.
|
25874495 |
2015 |
|
Malignant neoplasm of esophagus
|
|
0.010 |
GeneticVariation
|
BEFREE |
Long noncoding RNAs POLR2E rs3787016 C/T and HULC rs7763881 A/C polymorphisms are associated with decreased risk of esophageal cancer.
|
25874495 |
2015 |
|
Squamous cell carcinoma of esophagus
|
|
0.010 |
GeneticVariation
|
BEFREE |
We have genotyped the ANRIL rs2151280 T/C, POLR2E rs3787016 C/T, and HULC rs7763881 A/C SNPs in 380 esophageal squamous cell carcinoma (ESCC) cases and 380 cancer-free controls.
|
25874495 |
2015 |