| Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Macrothrombocytopenia and developmental delay with a de novo CDC42 mutation: Yet another locus for thrombocytopenia and developmental delay. | 26386261 | 2015 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties. | 24059268 | 2013 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. | 23382385 | 2013 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Expression analysis of Cdc42 in lung cancer and modulation of its expression by curcumin in lung cancer cell lines. | 22266952 | 2012 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Cdc42 in oncogenic transformation, invasion, and tumorigenesis. | 21515363 | 2011 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Local, persistent activation of Rho GTPases during plasticity of single dendritic spines. | 21423166 | 2011 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Cdc42 and vesicle trafficking in polarized cells. | 20633244 | 2010 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | RHO GTPase signaling for axon extension: is prenylation important? | 20878268 | 2010 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Kainic acid-induced F-344 rat model of mesial temporal lobe epilepsy: gene expression and canonical pathways. | 19700661 | 2009 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Further delineation of deletion 1p36 syndrome in 60 patients: a recognizable phenotype and common cause of developmental delay and mental retardation. | 18245432 | 2008 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation. | 19092927 | 2008 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Molecular basis of dendritic arborization. | 18511961 | 2008 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | GEFs and GAPs: critical elements in the control of small G proteins. | 17540168 | 2007 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Monosomy 1p36 deletion syndrome. | 17918734 | 2007 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma. | 17970806 | 2007 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. | 17050694 | 2006 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. | 16949823 | 2006 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Rho GTPases, dendritic structure, and mental retardation. | 15884002 | 2005 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Overexpression of RhoA, Rac1, and Cdc42 GTPases is associated with progression in testicular cancer. | 15269155 | 2004 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Structural basis of the Rho GTPase signaling. | 14561717 | 2003 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Development of a comparative genomic hybridization microarray and demonstration of its utility with 25 well-characterized 1p36 deletions. | 12915473 | 2003 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Physical map of 1p36, placement of breakpoints in monosomy 1p36, and clinical characterization of the syndrome. | 12687501 | 2003 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | The evolutionary history of effectors downstream of Cdc42 and Rac. | 11864373 | 2002 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation. | 12195014 | 2002 | |||||
Dysmorphic features
|
0.700 | CausalMutation | CLINVAR | Rho GTPases in cell biology. | 12478284 | 2002 |