|
Chronic Obstructive Airway Disease
|
|
0.880 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
|
26634245 |
2015 |
|
response to bronchodilator
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
|
26634245 |
2015 |
|
Forced expiratory volume function
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
|
26634245 |
2015 |
|
Adenocarcinoma of lung (disorder)
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
|
19836008 |
2009 |
|
Nasopharyngeal carcinoma
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
|
20512145 |
2010 |
|
Carcinoma of lung
|
|
0.800 |
GeneticVariation
|
BEFREE |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |
|
Malignant neoplasm of lung
|
|
0.800 |
GeneticVariation
|
BEFREE |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |
|
Malignant neoplasm of lung
|
|
0.800 |
GeneticVariation
|
GWASDB |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |
|
Carcinoma of lung
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |
|
Carcinoma of lung
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
|
18385738 |
2008 |
|
Malignant neoplasm of lung
|
|
0.800 |
GeneticVariation
|
GWASDB |
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
|
18385738 |
2008 |
|
Malignant neoplasm of urinary bladder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Among NHW, a significant association was found between rs8034191 and bladder cancer which persisted after adjustment for cigarette smoking status, number of cigarettes smoked per day and number of years of smoking (per C allele OR = 1.26; 95% CI, 1.04-1.54; P = 0.017).
|
21081471 |
2011 |
|
Carcinoma of bladder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Among NHW, a significant association was found between rs8034191 and bladder cancer which persisted after adjustment for cigarette smoking status, number of cigarettes smoked per day and number of years of smoking (per C allele OR = 1.26; 95% CI, 1.04-1.54; P = 0.017).
|
21081471 |
2011 |
|
Bladder Neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
Among NHW, a significant association was found between rs8034191 and bladder cancer which persisted after adjustment for cigarette smoking status, number of cigarettes smoked per day and number of years of smoking (per C allele OR = 1.26; 95% CI, 1.04-1.54; P = 0.017).
|
21081471 |
2011 |
|
Carcinoma of lung
|
|
0.800 |
GeneticVariation
|
BEFREE |
As a result, 15 SNPs on or near 12 genes and one miRNA with strong evidence of association with lung cancer risk were identified, including TERT (rs2736098), CHRNA3 (rs1051730), AGPHD1 (rs8034191), CLPTM1L (rs401681 and rs402710), BAT3 (rs3117582), TRNAA (rs4324798), ERCC2 (Lys751Gln), miR-146a2 (rs2910164), CYP1B1 (Arg48Gly), GSTM1 (null/present), SOD2 (C47T), IL-10 (-592C/A and -819C/T), and TP53 (intron 6).
|
29110844 |
2017 |
|
Malignant neoplasm of lung
|
|
0.800 |
GeneticVariation
|
BEFREE |
As a result, 15 SNPs on or near 12 genes and one miRNA with strong evidence of association with lung cancer risk were identified, including TERT (rs2736098), CHRNA3 (rs1051730), AGPHD1 (rs8034191), CLPTM1L (rs401681 and rs402710), BAT3 (rs3117582), TRNAA (rs4324798), ERCC2 (Lys751Gln), miR-146a2 (rs2910164), CYP1B1 (Arg48Gly), GSTM1 (null/present), SOD2 (C47T), IL-10 (-592C/A and -819C/T), and TP53 (intron 6).
|
29110844 |
2017 |
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
As a result, 15 SNPs on or near 12 genes and one miRNA with strong evidence of association with lung cancer risk were identified, including TERT (rs2736098), CHRNA3 (rs1051730), AGPHD1 (rs8034191), CLPTM1L (rs401681 and rs402710), BAT3 (rs3117582), TRNAA (rs4324798), ERCC2 (Lys751Gln), miR-146a2 (rs2910164), CYP1B1 (Arg48Gly), GSTM1 (null/present), SOD2 (C47T), IL-10 (-592C/A and -819C/T), and TP53 (intron 6).
|
29110844 |
2017 |
|
Malignant neoplasm of lung
|
|
0.800 |
GeneticVariation
|
GWASDB |
Common 5p15.33 and 6p21.33 variants influence lung cancer risk.
|
18978787 |
2008 |
|
Malignant neoplasm of lung
|
|
0.800 |
GeneticVariation
|
BEFREE |
Diplotype analysis of rs3841324 with either rs16969968 or rs8034191 showed that these polymorphisms influenced the lung cancer risk independently.
|
22028403 |
2011 |
|
Carcinoma of lung
|
|
0.800 |
GeneticVariation
|
BEFREE |
Diplotype analysis of rs3841324 with either rs16969968 or rs8034191 showed that these polymorphisms influenced the lung cancer risk independently.
|
22028403 |
2011 |
|
Primary malignant neoplasm of lung
|
|
0.100 |
GeneticVariation
|
BEFREE |
Diplotype analysis of rs3841324 with either rs16969968 or rs8034191 showed that these polymorphisms influenced the lung cancer risk independently.
|
22028403 |
2011 |
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
For the rs1051730 and rs8034191 polymorphisms, the results revealed that the five models were significantlyassociated with elevated risk of cancer.
|
27072204 |
2016 |
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
For the rs1051730 and rs8034191 polymorphisms, the results revealed that the five models were significantlyassociated with elevated risk of cancer.
|
27072204 |
2016 |
|
Malignant neoplasm of lung
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.
|
18385676 |
2008 |