|
Primary biliary cirrhosis
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.
|
22961000 |
2012 |
|
Primary biliary cirrhosis
|
|
0.800 |
GeneticVariation
|
GWASDB |
Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants.
|
22936693 |
2012 |
|
Primary biliary cirrhosis
|
|
0.800 |
GeneticVariation
|
GWASDB |
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.
|
22961000 |
2012 |
|
cervical cancer
|
|
0.720 |
GeneticVariation
|
BEFREE |
Analysis of rs8067378 Polymorphism in the Risk of Uterine Cervical Cancer from a Polish Population and its Impact on Gasdermin B Expression.
|
28120299 |
2017 |
|
cervical cancer
|
|
0.720 |
GeneticVariation
|
BEFREE |
In this study, associations between invasive cervical cancer and four cervical cancer susceptibility loci (rs13117307 at 4q12, rs8067378 at 17q12, and rs4282438 and rs9277952 at 6p21.32) in the Han Chinese population were investigated in a Japanese population.
|
27193219 |
2016 |
|
Asthma
|
|
0.720 |
GeneticVariation
|
BEFREE |
For ORMDL3-GSDMB region, rs8067378 (G allele protective against asthma) was correlated with decreased expression of GSDMB in BEC and BAL (P = 1.3 × 10(-4) and 0.04) but not ORMDL3. rs992969 in the promoter region of IL33 (A allele associated with higher eosinophil counts and risk for asthma) was correlated with increased expression of IL33 in BEC (P = 1.3 × 10(-6) ) but not in BAL.
|
26119467 |
2015 |
|
cervical cancer
|
|
0.720 |
GeneticVariation
|
GWASDB |
We identified strong evidence of associations between cervical cancer and two new loci: 4q12 (rs13117307, Pcombined, stringently matched=9.69×10(-9), per-allele odds ratio (OR)stringently matched=1.26) and 17q12 (rs8067378, Pcombined, stringently matched=2.00×10(-8), per-allele ORstringently matched=1.18).
|
23817570 |
2013 |
|
Asthma
|
|
0.720 |
GeneticVariation
|
BEFREE |
For two of these six loci (rs2305480 and rs8067378), there was evidence of association with asthma, and there was a weak association of asthma with rs8069176.
|
22370936 |
2012 |
|
Asthma
|
|
0.720 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
|
21804549 |
2011 |
|
Asthma
|
|
0.720 |
GeneticVariation
|
GWASDB |
A large-scale, consortium-based genomewide association study of asthma.
|
20860503 |
2010 |
|
Cervix carcinoma
|
|
0.710 |
GeneticVariation
|
BEFREE |
In this study, associations between invasive cervical cancer and four cervical cancer susceptibility loci (rs13117307 at 4q12, rs8067378 at 17q12, and rs4282438 and rs9277952 at 6p21.32) in the Han Chinese population were investigated in a Japanese population.
|
27193219 |
2016 |
|
Cervix carcinoma
|
|
0.710 |
GeneticVariation
|
GWASCAT |
We identified strong evidence of associations between cervical cancer and two new loci: 4q12 (rs13117307, Pcombined, stringently matched=9.69×10(-9), per-allele odds ratio (OR)stringently matched=1.26) and 17q12 (rs8067378, Pcombined, stringently matched=2.00×10(-8), per-allele ORstringently matched=1.18).
|
23817570 |
2013 |
|
Allergic Reaction
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
|
23817569 |
2013 |
|
Ulcerative Colitis
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
|
20228799 |
2010 |
|
Childhood asthma
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.
|
17611496 |
2007 |
|
Cervical Squamous Cell Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs13117307 C/T, rs8067378 A/G, rs4282438 G/T, and rs9277952 A/G SNPs were genotyped in 507 women with cervical squamous cell carcinoma (CSCC) and 432 age/sex matched healthy controls by using TaqMan PCR Assay.
|
30333560 |
2018 |
|
Squamous cell carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs8067378 SNP variants may increase the expression of GSDMB and the risk of the development and progression of cervical SCC.
|
28120299 |
2017 |
|
Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
We also found a significant association of the rs8067378 SNP with tumor stages III, IV, and grade of differentiation G3, and with parity, oral contraceptive use, smoking, and women of postmenopausal age.
|
28120299 |
2017 |
|
Malignant tumor of cervix
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, associations between invasive cervical cancer and four cervical cancer susceptibility loci (rs13117307 at 4q12, rs8067378 at 17q12, and rs4282438 and rs9277952 at 6p21.32) in the Han Chinese population were investigated in a Japanese population.
|
27193219 |
2016 |
|
Infiltrating Cervical Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Under a recessive model, the minor allele G of rs8067378 contributed to the risk of invasive cervical cancer (odds ratio=2.92, 95% confidence interval=1.40-6.36; P=0.0021).
|
27193219 |
2016 |