rs848, IL13;TH2LCRR

N. diseases: 8
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Allergic Reaction
CUI: C1527304
Disease: Allergic Reaction
0.700 GeneticVariation GWASCAT Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. 29083406 2017
Alopecia Areata
CUI: C0002171
Disease: Alopecia Areata
0.700 GeneticVariation GWASCAT Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci. 25608926 2015
Psoriasis
CUI: C0033860
Disease: Psoriasis
0.020 GeneticVariation BEFREE The authors genotyped three groups of Caucasians: those with PsA, those with psoriasis without arthritis (PsC) and healthy controls for the rs20541 and rs848 IL13 single nucleotide polymorphisms (SNPs). 21613309 2011
Arthritis, Psoriatic
CUI: C0003872
Disease: Arthritis, Psoriatic
0.020 GeneticVariation BEFREE The authors genotyped three groups of Caucasians: those with PsA, those with psoriasis without arthritis (PsC) and healthy controls for the rs20541 and rs848 IL13 single nucleotide polymorphisms (SNPs). 21613309 2011
Arthritis, Psoriatic
CUI: C0003872
Disease: Arthritis, Psoriatic
0.020 GeneticVariation BEFREE We examined the association between IL13 polymorphisms, smoking, and PsA in two Ps sample sets genotyped for rs1800925, rs20541, and rs848. 19554022 2009
Psoriasis
CUI: C0033860
Disease: Psoriasis
0.020 GeneticVariation BEFREE A multitiered genetic association study of 25 215 single-nucleotide polymorphisms (SNPs) in three case-control sample sets (1446 patients and 1432 controls) identified three IL13-linked SNPs (rs1800925, rs20541 and rs848) associated with psoriasis. 18075513 2008
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.010 GeneticVariation BEFREE Although the three SNPs showed no statistically significant associations with the risk and prognosis of CRC, a significant antagonistic interaction was found between rs848 (G-T) and allium vegetable intake (ORi (odds ratio of interaction), 0.92; 95% CI (confidence interval): 0.86, 0.99; P = 0.03); moreover, significant combined and synergistic interactions were observed for all three SNPs and overnight meal intake. 28537887 2017
Asthma
CUI: C0004096
Disease: Asthma
0.010 GeneticVariation BEFREE After adjusting for multiple testing and potential confounders, SNP rs848 in the IL13 gene region is significantly associated with a continuous measure of symptom severity in adult subjects with ever asthma. 26986948 2016
Wheezing
CUI: C0043144
Disease: Wheezing
0.010 GeneticVariation BEFREE SNP rs1800925, SNP rs20541 and SNP rs848 were significantly associated with increased risks on childhood wheeze with FDR of 0.03, 0.04 and 0.04, respectively. 23382814 2013
Arthritis
CUI: C0003864
Disease: Arthritis
0.010 GeneticVariation BEFREE The authors genotyped three groups of Caucasians: those with PsA, those with psoriasis without arthritis (PsC) and healthy controls for the rs20541 and rs848 IL13 single nucleotide polymorphisms (SNPs). 21613309 2011