|
Coronary Artery Disease
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
Coronary Artery Disease
|
|
0.810 |
GeneticVariation
|
BEFREE |
We identified 25 new SNP-CAD associations (P < 5 × 10<sup>-8</sup>, in fixed-effects meta-analysis) from 15 genomic regions, including SNPs in or near genes involved in cellular adhesion, leukocyte migration and atherosclerosis (PECAM1, rs1867624), coagulation and inflammation (PROCR, rs867186 (p.Ser219Gly)) and vascular smooth muscle cell differentiation (LMOD1, rs2820315).
|
28530674 |
2017 |
|
Coronary Artery Disease
|
|
0.810 |
GeneticVariation
|
GWASDB |
Large-scale association analysis identifies new risk loci for coronary artery disease.
|
23202125 |
2013 |
|
Factor VII measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
|
30642921 |
2019 |
|
Protein C measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities).
|
28082259 |
2017 |
|
Protein C antigen measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities).
|
28082259 |
2017 |
|
Protein C antigen measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic markers associated with plasma protein C level in African Americans: the atherosclerosis risk in communities (ARIC) study.
|
25376901 |
2014 |
|
Protein C measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic markers associated with plasma protein C level in African Americans: the atherosclerosis risk in communities (ARIC) study.
|
25376901 |
2014 |
|
Protein C antigen measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
For PC, we showed that two PROCR SNPs, rs867186 (Ser219Gly) and rs6060278, additionally explained c. 20% (P = 1·19 × 10(-31)) of the variance of plasma PC levels.
|
22443383 |
2012 |
|
Protein C measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
For PC, we showed that two PROCR SNPs, rs867186 (Ser219Gly) and rs6060278, additionally explained c. 20% (P = 1·19 × 10(-31)) of the variance of plasma PC levels.
|
22443383 |
2012 |
|
Protein C antigen measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study of the Protein C anticoagulant pathway.
|
22216198 |
2011 |
|
Protein C measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study of the Protein C anticoagulant pathway.
|
22216198 |
2011 |
|
Protein C measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study of the Protein C anticoagulant pathway.
|
22216198 |
2011 |
|
Protein C antigen measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study of the Protein C anticoagulant pathway.
|
22216198 |
2011 |
|
Protein C measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.
|
20802025 |
2010 |
|
Factor VII measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.
|
20231535 |
2010 |
|
Protein C antigen measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.
|
20802025 |
2010 |
|
Protein C antigen measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.
|
20802025 |
2010 |
|
Protein C measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.
|
20802025 |
2010 |
|
Factor VII measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.
|
20231535 |
2010 |
|
Coronary heart disease
|
|
0.720 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric analysis identifies novel variants for coronary artery disease.
|
21966275 |
2011 |
|
Coronary heart disease
|
|
0.720 |
GeneticVariation
|
BEFREE |
There was no association between PROCR Ser219Gly and risk of CHD, stroke, or mortality.
|
18680534 |
2008 |
|
Coronary heart disease
|
|
0.720 |
GeneticVariation
|
BEFREE |
We have progressively analysed three studies of coronary heart disease (CHD) for a variant in EPCR (Ser219Gly).
|
15921688 |
2005 |
|
Venous Thromboembolism
|
|
0.710 |
GeneticVariation
|
GWASCAT |
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.
|
31420334 |
2019 |
|
Venous Thromboembolism
|
|
0.710 |
GeneticVariation
|
BEFREE |
To determine if the maternal and paternal Ser219Gly dimorphism of the endothelial protein C receptor (EPCR), evaluated through detection of the PROCR 6936G allele, is a risk factor for VTE during pregnancy.
|
20141580 |
2010 |