rs9274407, HLA-DQB1

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Chemical and Drug Induced Liver Injury
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
0.800 GeneticVariation GWASCAT Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. 21570397 2011
Chemical and Drug Induced Liver Injury
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
0.800 GeneticVariation GWASDB Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. 21570397 2011
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.700 GeneticVariation GWASDB Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. 23242368 2013
Drug-Induced Liver Disease
CUI: C0860207
Disease: Drug-Induced Liver Disease
0.010 GeneticVariation BEFREE The strongest effect was with an HLA class II SNP (rs9274407, P=4.8×10(-14)), which correlated with rs3135388, a tag SNP of HLA-DRB1*1501-DQB1*0602 that was previously associated with AC-DILI. 21570397 2011