rs9468925, HLA-B

N. diseases: 5
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Vitiligo
CUI: C0042900
Disease: Vitiligo
0.820 GeneticVariation BEFREE Allele G of rs9468925 on HLA-C-HLA-B may be associated with a higher risk of vitiligo. 21951294 2012
Vitiligo
CUI: C0042900
Disease: Vitiligo
0.820 GeneticVariation BEFREE More importantly we find that rs9468925 in HLA-C/HLA-B is associated with both psoriasis and vitiligo, providing first important evidence that two major skin diseases share a common genetic locus in the MHC, and a basis for elucidating the molecular mechanism of skin disorders. 22125590 2011
Vitiligo
CUI: C0042900
Disease: Vitiligo
0.820 GeneticVariation GWASDB Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. 20526339 2010
Vitiligo
CUI: C0042900
Disease: Vitiligo
0.820 GeneticVariation GWASCAT Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. 20526339 2010
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
CUI: C1847835
Disease: VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
0.020 GeneticVariation BEFREE Allele G of rs9468925 on HLA-C-HLA-B may be associated with a higher risk of vitiligo. 21951294 2012
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
CUI: C1847835
Disease: VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
0.020 GeneticVariation BEFREE More importantly we find that rs9468925 in HLA-C/HLA-B is associated with both psoriasis and vitiligo, providing first important evidence that two major skin diseases share a common genetic locus in the MHC, and a basis for elucidating the molecular mechanism of skin disorders. 22125590 2011
Generalized vitiligo
CUI: C1304470
Disease: Generalized vitiligo
0.010 GeneticVariation BEFREE To explore the association between rs9468925 polymorphism within MHC and the clinical features of generalized vitiligo. 21951294 2012
Psoriasis
CUI: C0033860
Disease: Psoriasis
0.010 GeneticVariation BEFREE With four regression models obtained, two SNPs rs9468925 in HLA-C/HLA-B and rs2858881 in HLA-DQA2 were repeatedly selected in all models, suggesting that multiple loci outside PSOR1 locus were associated with psoriasis. 22125590 2011
Dermatologic disorders
CUI: C0037274
Disease: Dermatologic disorders
0.010 GeneticVariation BEFREE More importantly we find that rs9468925 in HLA-C/HLA-B is associated with both psoriasis and vitiligo, providing first important evidence that two major skin diseases share a common genetic locus in the MHC, and a basis for elucidating the molecular mechanism of skin disorders. 22125590 2011