Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PAPSS2 O95340 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Enzyme 2.0E-10 0.682 0.462 20
HACD1 B0YJ81 3-hydroxyacyl-CoA dehydratase 1 1.3E-09 0.539 0.846 45
HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase 1.1E-08 0.644 0.538 36
KDSR Q06136 3-ketodihydrosphingosine reductase 0.12 0.674 0.538 32
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 193
ABHD5 Q8WTS1 abhydrolase domain containing 5 6.4E-07 0.641 0.538 42
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 69
ASPM Q8IZT6 abnormal spindle microtubule assembly 3.4E-49 0.526 0.769 45
ACD Q96AP0 ACD shelterin complex subunit and telomerase recruitment factor 1.1E-12 0.603 0.731 47
ACP5 P13686 acid phosphatase 5, tartrate resistant 7.9E-02 0.561 0.731 44
ACTA1 P68133 actin alpha 1, skeletal muscle Cellular structure 1.1E-06 0.540 0.769 154
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 133
ACTL6B O94805 actin like 6B Cellular structure 2.8E-04 0.656 0.462 93
AUTS2 Q8WXX7 activator of transcription and developmental regulator AUTS2 1.00 0.569 0.846 112
ADNP Q9H2P0 activity dependent neuroprotector homeobox 1.00 0.561 0.808 138
ADAMTS10 Q9H324 ADAM metallopeptidase with thrombospondin type 1 motif 10 Enzyme 0.84 0.641 0.500 49
ADAMTS17 Q8TE56 ADAM metallopeptidase with thrombospondin type 1 motif 17 Enzyme 2.8E-15 0.678 0.385 18
ADAMTS2 O95450 ADAM metallopeptidase with thrombospondin type 1 motif 2 Enzyme 0.97 0.579 0.808 72
ADAMTSL2 Q86TH1 ADAMTS like 2 Enzyme 1.6E-03 0.666 0.346 40
AP1S2 P56377 adaptor related protein complex 1 subunit sigma 2 Transporter 0.87 0.631 0.615 65
AP3B2 Q13367 adaptor related protein complex 3 subunit beta 2 Transporter 0.77 0.691 0.346 55
AP4B1 Q9Y6B7 adaptor related protein complex 4 subunit beta 1 Transporter 1.3E-09 0.631 0.654 60
AP4E1 Q9UPM8 adaptor related protein complex 4 subunit epsilon 1 Receptor 2.8E-03 0.656 0.385 62
AP4M1 O00189 adaptor related protein complex 4 subunit mu 1 Extracellular structure 4.5E-17 0.638 0.500 63