Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 18
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 15
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846 7
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731 4
OGT O15294 O-linked N-acetylglucosamine (GlcNAc) transferase 1.00 0.626 0.731 4
MED1 Q15648 mediator complex subunit 1 1.00 0.573 0.692 3
RYR2 Q92736 ryanodine receptor 2 Ion channel 1.00 0.539 0.615 7
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885 3
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654 15
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808 15
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846 8
ENG P17813 endoglin 1.00 0.446 0.846 14
TOMM70 O94826 translocase of outer mitochondrial membrane 70 1.00 0.805 0.308 5
ACE2 Q9BYF1 angiotensin I converting enzyme 2 Enzyme 1.00 0.477 0.769 17
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885 42
SLC8A1 P32418 solute carrier family 8 member A1 Transporter 1.00 0.544 0.769 10
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808 9
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769 11
ARRB1 P49407 arrestin beta 1 Enzyme modulator 0.99 0.588 0.846 5
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846 15
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808 3
TUBB P07437 tubulin beta class I Cellular structure 0.98 0.603 0.692 10
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 47