Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 11 10
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 8 3
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 61 54
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 20 39
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 50 31
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 48 44
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 37 36
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 30 9
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846 15 22
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846 9 3
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 100 16
RREB1 Q92766 ras responsive element binding protein 1 1.00 0.500 0.808 27 23
HBB P68871 hemoglobin subunit beta 1.2E-09 0.494 0.808 19 2
PRDM16 Q9HAZ2 PR/SET domain 16 1.00 0.522 0.808 19 19
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808 18 9
WNT3 P56703 Wnt family member 3 Signaling 0.88 0.536 0.808 13 10
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808 10 7
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808 10 10
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 69 53
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 53 30
SLC39A8 Q9C0K1 solute carrier family 39 member 8 Transporter 0.67 0.584 0.769 38 8
TRPS1 Q9UHF7 transcriptional repressor GATA binding 1 1.00 0.537 0.769 24 33
SMAD7 O15105 SMAD family member 7 Transcription factor 0.55 0.470 0.769 21 13