Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATF3 P18847 activating transcription factor 3 Transcription factor 8.9E-02 0.494 0.885 30 1
ADAMTS1 Q9UHI8 ADAM metallopeptidase with thrombospondin type 1 motif 1 Enzyme 0.72 0.555 0.654 15 1
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 109 7
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769 27 10
AKR1C1 Q04828 aldo-keto reductase family 1 member C1 Enzyme 3.5E-15 0.593 0.615 18 1
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846 45 30
AREG P15514 amphiregulin Signaling 0.35 0.487 0.769 32 0
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 95 596
AVEN Q9NQS1 apoptosis and caspase activation inhibitor 2.7E-09 0.760 0.231 1 1
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 84 4
AXL P30530 AXL receptor tyrosine kinase Kinase 1.3E-02 0.489 0.615 16 3
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 115 90
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731 42 1
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731 108 72
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 109 1
CDH13 P55290 cadherin 13 7.1E-04 0.501 0.846 26 34
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731 11 0
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 58 9
CARD18 P57730 caspase recruitment domain family member 18 1.4E-03 0.861 0.154 2 0
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 171 2
CD74 P04233 CD74 molecule Enzyme modulator 0.25 0.512 0.808 8 0
CD9 P21926 CD9 molecule 4.7E-03 0.528 0.769 21 1
CERT1 Q9Y5P4 ceramide transporter 1 Transporter 0.67 0.674 0.500 8 16
CHFR Q96EP1 checkpoint with forkhead and ring finger domains Enzyme 7.9E-04 0.633 0.500 6 4