Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 241 7
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 192 93
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 184 9
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 119 12
LEP P41159 leptin 0.46 0.349 0.846 114 3
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 112 15
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 95 596
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 95 5
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 92 30
IL2 P60568 interleukin 2 0.48 0.336 0.885 75 3
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808 74 144
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 63 1
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 61 1
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 59 11
PAX6 P26367 paired box 6 1.00 0.450 0.769 55 109
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 48 6
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 48 0
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 45 8
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808 35 0
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769 34 1
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 34 6