Source: GWASDB

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 11 61
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 9 7
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 6 4
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 4 4
IL6 P05231 interleukin 6 0.32 0.248 0.962 3 1
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 1 1
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 4 4
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 4 2
GPX1 P07203 glutathione peroxidase 1 Enzyme 3.9E-05 0.458 0.923 3 1
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 3 1
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923 2 1
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 26 135
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885 12 22
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885 10 10
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885 7 3
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 6 4
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885 6 3
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885 6 4
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 5 1
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 4 5
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 3 3
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885 3 2
ELN P15502 elastin 2.1E-14 0.415 0.885 2 1
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 2 2