Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 38 13
IL6 P05231 interleukin 6 0.32 0.248 0.962 4 3
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 33 42
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 4 6
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885 14 34
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885 3 3
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885 2 2
CLU P10909 clusterin 7.8E-05 0.426 0.885 1 7
AICDA Q9GZX7 activation induced cytidine deaminase Enzyme 9.2E-06 0.463 0.885 1 1
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 50 31
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 32 19
CDH13 P55290 cadherin 13 7.1E-04 0.501 0.846 20 29
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846 19 29
CNTNAP2 Q9UHC6 contactin associated protein 2 2.9E-09 0.530 0.846 11 13
DST Q03001 dystonin Cellular structure 1.00 0.552 0.846 6 5
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 4 4
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 3 3
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808 16 16
COL18A1 P39060 collagen type XVIII alpha 1 chain 1.7E-10 0.449 0.808 7 18
PTK2B Q14289 protein tyrosine kinase 2 beta Kinase 0.94 0.448 0.808 6 7
LAMA1 P25391 laminin subunit alpha 1 3.2E-32 0.582 0.808 3 4
CR1 P17927 complement C3b/C4b receptor 1 (Knops blood group) 1.6E-35 0.533 0.808 2 8
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808 1 1
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769 17 44