Source: HPO

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 119
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 264
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 154
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 206
DMD P11532 dystrophin 1.00 0.423 0.923 86
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 193
INS P01308 insulin 0.30 0.445 0.923 73
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846 58
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 219
NKX2-1 P43699 NK2 homeobox 1 Transcription factor 0.36 0.457 0.808 80
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808 77
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846 126
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808 53
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731 21
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846 108
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769 50
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 198
EZR P15311 ezrin Cellular structure 0.18 0.476 0.808 39
ARG1 P05089 arginase 1 Enzyme 3.6E-04 0.476 0.846 19
PAX8 Q06710 paired box 8 1.00 0.477 0.731 37
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846 26
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 62
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808 40
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 103