| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
|---|---|---|---|---|---|---|---|
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 | 138 |
| TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 | 101 |
| CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 | 94 |
| IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | 92 | |
| PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 | 76 |
| ICAM1 | P05362 | intercellular adhesion molecule 1 | 3.5E-02 | 0.364 | 0.962 | 55 | |
| IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | 54 | |
| TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 | 42 |
| CAT | P04040 | catalase | Enzyme | 1.6E-10 | 0.359 | 0.962 | 41 |
| TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | 41 | |
| IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | 36 | |
| APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | 34 | |
| IL4 | P05112 | interleukin 4 | 4.7E-03 | 0.332 | 0.962 | 32 | |
| SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 | 23 |
| CRP | P02741 | C-reactive protein | 3.7E-03 | 0.299 | 0.962 | 22 | |
| ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 | 22 |
| IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | 19 | |
| FN1 | P02751 | fibronectin 1 | Signaling | 1.4E-03 | 0.365 | 0.962 | 16 |
| APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | 15 | |
| AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 | 12 |
| ALB | P02768 | albumin | Transporter | 0.64 | 0.317 | 0.962 | 10 |
| NLRP3 | Q96P20 | NLR family pyrin domain containing 3 | 8.1E-04 | 0.361 | 0.962 | 10 | |
| CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 | 9 |
| CD44 | P16070 | CD44 molecule (Indian blood group) | 2.4E-07 | 0.363 | 0.962 | 6 |