Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PECAM1 P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 0.426 0.846 14
DEFA1 P59665 defensin alpha 1 0.636 0.731 10
PYDC1 Q8WXC3 pyrin domain containing 1 0.805 0.192 1
DMBT1 Q9UGM3 deleted in malignant brain tumors 1 Enzyme 4.5E-63 0.533 0.654 10
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885 21
SELP P16109 selectin P 5.0E-32 0.460 0.769 25
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 25
SLC28A2 O43868 solute carrier family 28 member 2 Transporter 1.1E-27 0.780 0.385 2
F11 P03951 coagulation factor XI Enzyme 3.6E-26 0.590 0.692 6
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885 27
C5 P01031 complement C5 Enzyme modulator 8.1E-24 0.550 0.731 9
SLC28A3 Q9HAS3 solute carrier family 28 member 3 Transporter 2.7E-23 0.674 0.615 2
ITIH2 P19823 inter-alpha-trypsin inhibitor heavy chain 2 Enzyme modulator 3.8E-23 0.839 0.308 3
LTF P02788 lactotransferrin Enzyme 1.3E-21 0.543 0.846 13
SCUBE2 Q9NQ36 signal peptide, CUB domain and EGF like domain containing 2 Extracellular structure 3.6E-21 0.743 0.231 2
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846 12
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 27
NOD1 Q9Y239 nucleotide binding oligomerization domain containing 1 Enzyme 2.5E-18 0.541 0.769 7
TGM2 P21980 transglutaminase 2 Enzyme 6.8E-18 0.445 0.808 19
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 48
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 149
CPB2 Q96IY4 carboxypeptidase B2 Enzyme 2.7E-17 0.536 0.846 21
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 27
SERPINB4 P48594 serpin family B member 4 Enzyme modulator 8.8E-17 0.623 0.423 7