Source: UNIPROT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885 3 1
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 7 45
TEX14 Q8IWB6 testis expressed 14, intercellular bridge forming factor Kinase 9.1E-36 0.780 0.231 1 0
EPHA10 Q5JZY3 EPH receptor A10 Kinase 1.2E-26 0.780 0.192 2 1
TRPM7 Q96QT4 transient receptor potential cation channel subfamily M member 7 Ion channel 5.2E-16 0.531 0.731 3 1
MLKL Q8NB16 mixed lineage kinase domain like pseudokinase Kinase 2.1E-14 0.570 0.731 1 1
TNK2 Q07912 tyrosine kinase non receptor 2 Kinase 8.2E-12 0.623 0.538 4 2
EPHA8 P29322 EPH receptor A8 Kinase 1.8E-10 0.686 0.346 4 0
BRDT Q58F21 bromodomain testis associated Epigenetic regulator 5.8E-09 0.751 0.231 2 2
ITK Q08881 IL2 inducible T cell kinase Kinase 3.1E-08 0.555 0.769 3 2
PRKAA2 P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 3.5E-08 0.456 0.846 2 0
WEE2 P0C1S8 WEE2 oocyte meiosis inhibiting kinase 4.8E-06 0.890 0.154 2 1
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731 2 5
EPHA2 P29317 EPH receptor A2 Kinase 1.1E-05 0.501 0.731 2 4
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 6 35
GRK6 P43250 G protein-coupled receptor kinase 6 Kinase 4.9E-04 0.670 0.654 2 6
AXL P30530 AXL receptor tyrosine kinase Kinase 1.3E-02 0.489 0.615 1 1
EPHB4 P54760 EPH receptor B4 Kinase 1.3E-02 0.524 0.692 4 13
MAP3K9 P80192 mitogen-activated protein kinase kinase kinase 9 Kinase 0.12 0.711 0.269 2 1
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846 6 19
STK26 Q9P289 serine/threonine kinase 26 Kinase 0.31 0.705 0.538 1 0
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 2 0
MARK1 Q9P0L2 microtubule affinity regulating kinase 1 Kinase 0.60 0.663 0.577 2 0