Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1801 22
IFNG P01579 interferon gamma 0.47 0.288 0.962 1519 11
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1368 68
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1074 19
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 1049 62
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 1002 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 996 23
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 985 137
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 750 18
MIR21 microRNA 21 0.363 0.846 726 2
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 706 308
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 693 64
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 687 4
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 679 45
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 672 82
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 666 9
VIM P08670 vimentin 0.71 0.372 0.846 644 6
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 627 9
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 610 18
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885 551 9