Source: CGI

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808 3
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577 3
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 39
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731 3
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 5
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808 6
SBDS Q9Y3A5 SBDS ribosome maturation factor Enzyme 6.2E-05 0.601 0.692 2
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 1
ARHGAP26 Q9UNA1 Rho GTPase activating protein 26 Enzyme modulator 1.00 0.656 0.500 3
RAD21 O60216 RAD21 cohesin complex component 1.00 0.528 0.846 8
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 3
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769 8
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846 3
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 17
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 15
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 33
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 16
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 7
JAK1 P23458 Janus kinase 1 Kinase 1.00 0.474 0.769 3
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808 5
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808 9
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 29
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654 1
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654 2