Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 135
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 133
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 330
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 266
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 94
LMNA P02545 lamin A/C 1.00 0.384 0.885 468
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 224
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846 125
PTCH1 Q13635 patched 1 1.00 0.398 0.885 262
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 82
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 140
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 217
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846 65
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 49
ELN P15502 elastin 2.1E-14 0.415 0.885 257
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846 122
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 327
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808 51
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 147
FLNA P21333 filamin A 1.00 0.419 0.846 298