Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 133
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 153
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 51
LMNA P02545 lamin A/C 1.00 0.384 0.885 468
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923 52
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 170
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923 26
PTCH1 Q13635 patched 1 1.00 0.398 0.885 262
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846 44
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 327
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846 191
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 52
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 281
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885 98
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 236
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808 149
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885 38
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 121
NKX2-1 P43699 NK2 homeobox 1 Transcription factor 0.36 0.457 0.808 85
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808 140
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 47
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846 165