Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LMNA P02545 lamin A/C 1.00 0.384 0.885 425
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 219
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 214
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 202
TRNL1 tRNA 0.534 0.731 194
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808 188
TRNW tRNA 0.563 0.731 175
PEX1 O43933 peroxisomal biogenesis factor 1 1.1E-14 0.538 0.769 171
TRNS1 tRNA 0.555 0.808 170
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692 168
RNU4ATAC RNA, U4atac small nuclear (U12-dependent splicing) 0.556 0.808 167
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808 155
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 154
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731 153
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769 151
GPC4 O75487 glypican 4 0.93 0.547 0.769 148
WDR35 Q9P2L0 WD repeat domain 35 1.0E-22 0.525 0.692 148
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 147
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846 142
RMRP RNA component of mitochondrial RNA processing endoribonuclease 0.519 0.731 141
PEX2 P28328 peroxisomal biogenesis factor 2 2.6E-04 0.582 0.654 137
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 128
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 127
GPC3 P51654 glypican 3 1.00 0.466 0.808 126