Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 340 9
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 232 407
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 171 2
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 113 95
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 109 7
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 109 1
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 103 3
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 44 22
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 285 1
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 184 9
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 182 355
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 164 35
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 138 9
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 138 40
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 137 3
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 108 98
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 99 10
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 98 8
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 98 61