Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 18
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 40
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 6
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 20
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 40
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 26
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 11
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 20
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 20
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885 10
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 33
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 30
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846 31
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 21
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 21
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846 24
FOXO1 Q12778 forkhead box O1 1.00 0.433 0.846 4
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40