Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 94 101
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 74 50
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 53 30
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 52 70
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 48 44
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769 46 41
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.539 0.731 41 29
DLEU1 O43261 deleted in lymphocytic leukemia 1 0.47 0.569 0.692 38 64
MIR4435-2HG MIR4435-2 host gene 0.604 0.692 38 56
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 35 48
CASC15 cancer susceptibility 15 0.603 0.577 35 41
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 34 1
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615 33 44
CCDC26 Q8TAB7 CCDC26 long non-coding RNA 0.647 0.615 31 41
GLIS3 Q8NEA6 GLIS family zinc finger 3 5.6E-08 0.590 0.654 31 36
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 31 11
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846 29 32
PNKD Q8N490 PNKD metallo-beta-lactamase domain containing 4.1E-08 0.615 0.615 28 17
NOTCH4 Q99466 notch receptor 4 2.1E-23 0.534 0.731 27 20
PVT1 Pvt1 oncogene 0.495 0.731 27 31
RREB1 Q92766 ras responsive element binding protein 1 1.00 0.500 0.808 27 23