Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808 4
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 12
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808 2
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538 9
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 10
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846 9
CHRNA2 Q15822 cholinergic receptor nicotinic alpha 2 subunit Ion channel 6.5E-10 0.705 0.385 3
CRY1 Q16526 cryptochrome circadian regulator 1 Enzyme 1.7E-09 0.585 0.769 4
NPSR1 Q6W5P4 neuropeptide S receptor 1 2.1E-09 0.608 0.615 4
FOLH1 Q04609 folate hydrolase 1 Enzyme 6.2E-09 0.453 0.885 3
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808 2
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577 13
LTA4H P09960 leukotriene A4 hydrolase 3.0E-08 0.617 0.654 2
CHRNA6 Q15825 cholinergic receptor nicotinic alpha 6 subunit Ion channel 3.6E-08 0.711 0.346 4
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 3
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 4
SLC29A3 Q9BZD2 solute carrier family 29 member 3 Transporter 1.3E-07 0.578 0.769 2
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 6
HTR3B O95264 5-hydroxytryptamine receptor 3B Ion channel 2.5E-07 0.678 0.423 7
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654 12
TPH1 P17752 tryptophan hydroxylase 1 3.2E-07 0.553 0.731 9
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 3
SERPINA6 P08185 serpin family A member 6 Enzyme modulator 8.3E-07 0.606 0.731 2
ADCY7 P51828 adenylate cyclase 7 9.5E-07 0.656 0.462 6