Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PGF P49763 placental growth factor Signaling 0.13 0.460 0.846 11
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 9
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 17
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846 23
LIF P15018 LIF interleukin 6 family cytokine Signaling 0.52 0.483 0.769 4
SIRT3 Q9NTG7 sirtuin 3 Epigenetic regulator 1.6E-04 0.488 0.731 9
MMP8 P22894 matrix metallopeptidase 8 Enzyme 1.1E-24 0.488 0.808 2
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808 2
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808 18
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731 13
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22
APLN Q9ULZ1 apelin 0.46 0.497 0.769 7
DDR1 Q08345 discoidin domain receptor tyrosine kinase 1 Kinase 4.6E-06 0.497 0.808 2
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846 4
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 17
HSF1 Q00613 heat shock transcription factor 1 Transcription factor 0.75 0.507 0.769 12
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846 14
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731 2
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808 20
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654 3
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692 8
FOSL1 P15407 FOS like 1, AP-1 transcription factor subunit Transcription factor 0.16 0.519 0.846 5
BNIP3 Q12983 BCL2 interacting protein 3 2.0E-05 0.520 0.731 14