Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 53 5
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 51 62
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 51 5
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846 50 34
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 49 33
GNB3 P16520 G protein subunit beta 3 Enzyme 3.3E-11 0.518 0.808 49 4
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 48 6
BDKRB2 P30411 bradykinin receptor B2 G-protein coupled receptor 0.12 0.585 0.808 48 1
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 48 0
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 45 8
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 45 1
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 44 5
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 44 0
ATP7B P35670 ATPase copper transporting beta Transporter 4.8E-30 0.529 0.654 43 320
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846 43 58
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 43 12
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808 42 14
SLC6A2 P23975 solute carrier family 6 member 2 Transporter 8.2E-02 0.490 0.846 41 2
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885 39 91
GRM1 Q13255 glutamate metabotropic receptor 1 G-protein coupled receptor 0.14 0.528 0.808 39 7
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846 39 2
HTR7 P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 4.5E-02 0.592 0.500 39 0
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769 38 33
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808 38 1