Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 731 141
MIR21 microRNA 21 0.363 0.846 726 2
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 724 33
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 724 10
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 721 25
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 715 92
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 711 47
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 706 308
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 703 681
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 703 97
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 702 98
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846 702 30
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 701 52
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 698 29
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 693 64
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 689 68
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 688 27
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 687 76
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 687 4
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 684 974
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 679 45