Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 69
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 58
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846 31
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 30
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 28
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 21
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769 20
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 19
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885 19
ARG1 P05089 arginase 1 Enzyme 3.6E-04 0.476 0.846 17
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846 17
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 16
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808 16
OTC P00480 ornithine carbamoyltransferase 0.87 0.565 0.846 15
ENG P17813 endoglin 1.00 0.446 0.846 12
TJP1 Q07157 tight junction protein 1 Cell-cell junction 1.00 0.576 0.692 11
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577 9
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 9
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885 8
LAMP2 P13473 lysosomal associated membrane protein 2 Transporter 0.27 0.552 0.731 8