| PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
23
|
| TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
19
|
| SMAD4 |
Q13485
|
SMAD family member 4
|
Transcription factor
|
1.00 |
0.401 |
0.808 |
13
|
| NRAS |
P01111
|
NRAS proto-oncogene, GTPase
|
Enzyme modulator
|
0.49 |
0.390 |
0.808 |
10
|
| MSH2 |
P43246
|
mutS homolog 2
|
Nucleic acid binding
|
0.90 |
0.406 |
0.808 |
9
|
| MSH6 |
P52701
|
mutS homolog 6
|
Nucleic acid binding
|
3.7E-05 |
0.462 |
0.731 |
9
|
| MLH1 |
P40692
|
mutL homolog 1
|
Nucleic acid binding
|
3.4E-05 |
0.399 |
0.808 |
8
|
| PMS2 |
P54278
|
PMS1 homolog 2, mismatch repair system component
|
Nucleic acid binding
|
4.5E-27 |
0.484 |
0.808 |
7
|
| AKT1 |
P31749
|
AKT serine/threonine kinase 1
|
Kinase
|
0.98 |
0.311 |
0.962 |
6
|
| CHEK2 |
O96017
|
checkpoint kinase 2
|
Kinase
|
1.2E-24 |
0.460 |
0.808 |
5
|
| APC |
P25054
|
APC regulator of WNT signaling pathway
|
|
1.00 |
0.373 |
0.962 |
4
|
| MUTYH |
Q9UIF7
|
mutY DNA glycosylase
|
Enzyme
|
1.3E-18 |
0.521 |
0.769 |
4
|
| POLD1 |
P28340
|
DNA polymerase delta 1, catalytic subunit
|
|
2.4E-06 |
0.507 |
0.769 |
4
|
| BMPR1A |
P36894
|
bone morphogenetic protein receptor type 1A
|
Kinase
|
0.90 |
0.522 |
0.731 |
3
|
| POLE |
Q07864
|
DNA polymerase epsilon, catalytic subunit
|
|
8.0E-27 |
0.526 |
0.731 |
3
|
| CCND1 |
P24385
|
cyclin D1
|
Enzyme modulator
|
0.89 |
0.344 |
0.923 |
2
|
| NTHL1 |
P78549
|
nth like DNA glycosylase 1
|
Enzyme
|
5.7E-10 |
0.623 |
0.615 |
2
|
| STK11 |
Q15831
|
serine/threonine kinase 11
|
Kinase
|
0.99 |
0.435 |
0.808 |
2
|