Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SLC22A5 O76082 solute carrier family 22 member 5 Transporter 5.3E-16 0.608 0.731 7
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 7
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 4
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 3
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 2
IL12B P29460 interleukin 12B Signaling 1.1E-04 0.480 0.885 2
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769 2
IRGM A1A4Y4 immunity related GTPase M 0.617 0.538 2
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808 2
SLC22A4 Q9H015 solute carrier family 22 member 4 Transporter 1.8E-08 0.603 0.769 2
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769 2
ATG16L1 Q676U5 autophagy related 16 like 1 0.96 0.543 0.769 1
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1
MUC2 Q02817 mucin 2, oligomeric mucus/gel-forming Enzyme modulator 9.4E-10 0.486 0.808 1