Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 330
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 326
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 283
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 281
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846 279
ELN P15502 elastin 2.1E-14 0.415 0.885 257
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 236
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 232
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 221
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 220
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 217
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769 214
TRNL1 tRNA 0.534 0.731 213
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808 207
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731 202
VCP P55072 valosin containing protein 1.00 0.469 0.923 198
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808 196
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769 195
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 192
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846 192
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 190
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808 187