Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 48
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846 26
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 25
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 20
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 16
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846 16
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769 15
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846 10
SPARC P09486 secreted protein acidic and cysteine rich Signaling 0.89 0.445 0.846 8
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692 4
MYOC Q99972 myocilin Cellular structure 7.6E-12 0.595 0.500 3
CCR6 P51684 C-C motif chemokine receptor 6 G-protein coupled receptor 5.8E-03 0.485 0.808 2
CDK2 P24941 cyclin dependent kinase 2 Kinase 0.61 0.456 0.692 2
CXCR1 P25024 C-X-C motif chemokine receptor 1 G-protein coupled receptor 3.0E-07 0.508 0.769 1
PFN1 P07737 profilin 1 0.73 0.565 0.769 1