Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
INS P01308 insulin 0.30 0.445 0.923 153
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 133
LEP P41159 leptin 0.46 0.349 0.846 104
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885 57
TFRC P02786 transferrin receptor Enzyme 7.0E-05 0.437 0.885 51
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 48
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885 47
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885 45
DMD P11532 dystrophin 1.00 0.423 0.923 36
LMNA P02545 lamin A/C 1.00 0.384 0.885 36
RBP4 P02753 retinol binding protein 4 Transporter 0.52 0.493 0.808 32
LHB P01229 luteinizing hormone subunit beta Signaling 2.2E-03 0.638 0.462 29
RUNX3 Q13761 RUNX family transcription factor 3 Transcription factor 0.84 0.459 0.731 27
SCNN1A P37088 sodium channel epithelial 1 subunit alpha Ion channel 1.1E-11 0.601 0.577 24
AKR1C3 P42330 aldo-keto reductase family 1 member C3 Enzyme 7.6E-24 0.529 0.769 23
BCL11A Q9H165 BAF chromatin remodeling complex subunit BCL11A Transcription factor 0.97 0.541 0.769 22
MALAT1 metastasis associated lung adenocarcinoma transcript 1 0.435 0.846 22
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731 22
LIF P15018 LIF interleukin 6 family cytokine Signaling 0.52 0.483 0.769 21
AKR1C2 P52895 aldo-keto reductase family 1 member C2 Enzyme 6.9E-11 0.608 0.577 19
AKR1C1 Q04828 aldo-keto reductase family 1 member C1 Enzyme 3.5E-15 0.593 0.615 18
HSD3B2 P26439 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Enzyme 7.2E-08 0.582 0.500 15
AZGP1 P25311 alpha-2-glycoprotein 1, zinc-binding 4.2E-06 0.566 0.769 13
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 12