Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 340 9
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 285 1
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 241 7
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 167 4
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 151 0
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 146 14
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 138 5
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 137 3
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 130 54
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 119 12
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 113 9
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 96 6
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 81 2
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 80 6
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 73 6
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 70 0
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 66 6
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 64 6
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 63 0
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 57 9
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 53 22