Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 327
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 229
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808 171
TRIP11 Q15643 thyroid hormone receptor interactor 11 1.7E-12 0.595 0.654 133
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846 113
XYLT1 Q86Y38 xylosyltransferase 1 0.92 0.581 0.731 101
CANT1 Q8WVQ1 calcium activated nucleotidase 1 2.5E-06 0.619 0.731 79
FGD1 P98174 FYVE, RhoGEF and PH domain containing 1 Enzyme modulator 1.00 0.573 0.731 79
COMP P49747 cartilage oligomeric matrix protein 1.3E-09 0.503 0.808 73
ANO5 Q75V66 anoctamin 5 2.9E-22 0.619 0.538 72
SH3PXD2B A1X283 SH3 and PX domains 2B 4.2E-03 0.631 0.577 71
CTDP1 Q9Y5B0 CTD phosphatase subunit 1 Enzyme 6.0E-04 0.641 0.577 65
GRIA3 P42263 glutamate ionotropic receptor AMPA type subunit 3 Ion channel 1.00 0.566 0.692 64
AP4M1 O00189 adaptor related protein complex 4 subunit mu 1 Extracellular structure 4.5E-17 0.638 0.500 63
AP4E1 Q9UPM8 adaptor related protein complex 4 subunit epsilon 1 Receptor 2.8E-03 0.656 0.385 62
AP4B1 Q9Y6B7 adaptor related protein complex 4 subunit beta 1 Transporter 1.3E-09 0.631 0.654 60
AP4S1 Q9Y587 adaptor related protein complex 4 subunit sigma 1 Transporter 1.7E-06 0.674 0.385 58
MCOLN1 Q9GZU1 mucolipin 1 Ion channel 5.8E-04 0.601 0.654 57
CDT1 Q9H211 chromatin licensing and DNA replication factor 1 2.6E-10 0.597 0.731 55
SLC6A9 P48067 solute carrier family 6 member 9 Transporter 2.2E-05 0.641 0.500 38