| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
|---|---|---|---|---|---|---|---|
| BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 | 254 |
| GJA1 | P17302 | gap junction protein alpha 1 | Cell-cell junction | 0.16 | 0.393 | 0.885 | 205 |
| NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 | 186 |
| MBTPS2 | O43462 | membrane bound transcription factor peptidase, site 2 | Enzyme | 1.00 | 0.513 | 0.769 | 163 |
| SOS1 | Q07889 | SOS Ras/Rac guanine nucleotide exchange factor 1 | Enzyme modulator | 1.00 | 0.485 | 0.808 | 73 |
| WNT10A | Q9GZT5 | Wnt family member 10A | Signaling | 4.2E-09 | 0.547 | 0.731 | 52 |
| KRT16 | P08779 | keratin 16 | 1.5E-14 | 0.565 | 0.769 | 27 | |
| KRT83 | P78385 | keratin 83 | 3.4E-14 | 0.716 | 0.269 | 26 | |
| KDF1 | Q8NAX2 | keratinocyte differentiation factor 1 | 0.15 | 0.729 | 0.269 | 21 | |
| KRT81 | Q14533 | keratin 81 | 1.2E-18 | 0.659 | 0.462 | 21 | |
| KRT86 | O43790 | keratin 86 | 3.6E-07 | 0.736 | 0.308 | 21 | |
| LRP1 | Q07954 | LDL receptor related protein 1 | 1.00 | 0.482 | 0.769 | 10 |