Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 74 50
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 69 53
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 53 30
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 50 31
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 45 46
SLC39A8 Q9C0K1 solute carrier family 39 member 8 Transporter 0.67 0.584 0.769 38 8
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 36 16
CUX2 O14529 cut like homeobox 2 Transcription factor 1.00 0.644 0.500 36 10
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615 33 44
ZFHX3 Q15911 Q6ZP98 zinc finger homeobox 3 0.45 0.621 0.654 32 34
GLIS3 Q8NEA6 GLIS family zinc finger 3 5.6E-08 0.590 0.654 31 36
SIK3 Q9Y2K2 SIK family kinase 3 Kinase 1.00 0.631 0.654 28 20
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654 28 15
MAML3 Q96JK9 mastermind like transcriptional coactivator 3 Transcription factor 1.00 0.653 0.577 28 10
CELSR2 Q9HCU4 cadherin EGF LAG seven-pass G-type receptor 2 G-protein coupled receptor 1.00 0.656 0.577 26 8
ATP2B1 P20020 ATPase plasma membrane Ca2+ transporting 1 Transporter 1.00 0.666 0.500 25 19
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731 24 12
ITPK1 Q13572 inositol-tetrakisphosphate 1-kinase Kinase 0.99 0.760 0.346 23 8
SUGP1 Q8IWZ8 SURP and G-patch domain containing 1 Nucleic acid binding 1.00 0.623 0.615 23 6
PLCG1 P19174 phospholipase C gamma 1 Enzyme 7.9E-05 0.564 0.692 22 6
SPC25 Q9HBM1 SPC25 component of NDC80 kinetochore complex 2.6E-02 0.729 0.346 20 16
POLK Q9UBT6 DNA polymerase kappa 7.5E-13 0.691 0.423 20 4