Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 71
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 59
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808 37
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 35
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 26
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 21
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769 20
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846 20
ACE2 Q9BYF1 angiotensin I converting enzyme 2 Enzyme 1.00 0.477 0.769 17
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 17
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 17
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885 17
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808 15
CFL1 P23528 cofilin 1 0.56 0.529 0.769 14
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769 13