Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ENPP1 P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 5.0E-08 0.498 0.808 106
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 92
ABCC6 O95255 ATP binding cassette subfamily C member 6 Transporter 5.6E-35 0.540 0.654 88
ATXN1 P54253 ataxin 1 0.97 0.534 0.769 83
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 79
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846 71
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808 69
SLC20A2 Q08357 solute carrier family 20 member 2 Transporter 0.97 0.638 0.577 65
TMEM258 P61165 transmembrane protein 258 1.9E-03 0.644 0.654 62
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885 61
ST3GAL3 Q11203 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 2.6E-03 0.606 0.654 61
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769 54
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 52
COL4A2 P08572 collagen type IV alpha 2 chain 3.6E-15 0.563 0.654 45
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 41
PHACTR1 Q9C0D0 phosphatase and actin regulator 1 Enzyme modulator 0.64 0.663 0.423 38
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 38
HGD Q93099 homogentisate 1,2-dioxygenase Enzyme 3.0E-08 0.631 0.577 37
PDSS2 Q86YH6 decaprenyl diphosphate synthase subunit 2 4.4E-08 0.626 0.577 36
DOCK7 Q96N67 dedicator of cytokinesis 7 Enzyme modulator 6.4E-06 0.682 0.423 33
ALDH7A1 P49419 aldehyde dehydrogenase 7 family member A1 Enzyme 1.4E-22 0.551 0.769 32
FRY Q5TBA9 FRY microtubule binding protein 1.00 0.666 0.500 24
LRP1B Q9NZR2 LDL receptor related protein 1B 2.5E-06 0.626 0.615 23
SPC25 Q9HBM1 SPC25 component of NDC80 kinetochore complex 2.6E-02 0.729 0.346 22