| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
|---|---|---|---|---|---|---|---|
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 | 16 |
| POT1 | Q9NUX5 | protection of telomeres 1 | Nucleic acid binding | 0.85 | 0.560 | 0.731 | 6 |
| ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 | 5 |
| CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 | 5 |
| ARL11 | Q969Q4 | ADP ribosylation factor like GTPase 11 | 5.3E-03 | 0.670 | 0.423 | 3 | |
| IGHG1 | P01857 | immunoglobulin heavy constant gamma 1 (G1m marker) | 0.700 | 0.500 | 3 | ||
| IGHV3-21 | A0A0B4J1V1 | immunoglobulin heavy variable 3-21 | 0.780 | 0.192 | 3 | ||
| IKZF3 | Q9UKT9 | IKAROS family zinc finger 3 | Transcription factor | 0.98 | 0.608 | 0.692 | 3 |
| P2RX7 | Q99572 | purinergic receptor P2X 7 | Ion channel | 3.3E-11 | 0.450 | 0.808 | 3 |
| RPS15 | P62841 | ribosomal protein S15 | Nucleic acid binding | 0.83 | 0.695 | 0.231 | 3 |