Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808 9
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 7
POT1 Q9NUX5 protection of telomeres 1 Nucleic acid binding 0.85 0.560 0.731 6
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 6
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731 5
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808 4
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808 3
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885 3
ACD Q96AP0 ACD shelterin complex subunit and telomerase recruitment factor 1.1E-12 0.603 0.731 2
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769 2
TERF2IP Q9NYB0 TERF2 interacting protein 2.7E-05 0.548 0.731 1