| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
superoxide dismutase 1 | 0.379 | 0.962 | 0.18 |
|
disease | 0.800 | strong | 0.985 | 60 | 0 | 1993 | 2020 | ||||||||
|
TAR DNA binding protein | 0.493 | 0.808 | 0.99 |
|
disease | 0.700 | None | 0.979 | 15 | 0 | 2006 | 2020 | ||||||||
|
paraoxonase 1 | 0.409 | 0.885 | 9.8E-11 |
|
disease | 0.700 | None | 0.929 | 3 | 0 | 2007 | 2019 | ||||||||
|
FUS RNA binding protein | 0.470 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.981 | 2 | 0 | 2009 | 2020 | ||||||||
|
neurofilament heavy | 0.588 | 0.769 | 2.7E-12 |
|
disease | 0.500 | None | 1.000 | 2 | 0 | 1993 | 2018 | ||||||||
|
angiogenin | 0.511 | 0.769 | 0.29 |
|
disease | 0.500 | None | 0.959 | 2 | 0 | 2004 | 2019 | ||||||||
|
peripherin | 0.623 | 0.462 | 4.8E-14 |
|
disease | 0.500 | None | 1.000 | 1 | 0 | 2000 | 2016 | ||||||||
|
VAMP associated protein B and C | 0.666 | 0.423 | 0.58 |
|
disease | 0.500 | None | 0.967 | 1 | 0 | 2004 | 2019 | ||||||||
|
senataxin | 0.570 | 0.731 | 0.95 |
|
disease | 0.500 | moderate | 0.952 | 1 | 0 | 1998 | 2018 | ||||||||
|
dipeptidyl peptidase like 6 | 0.603 | 0.692 | 0.34 |
|
disease | 0.470 | None | 0.857 | 1 | 0 | 2008 | 2013 | ||||||||
|
solute carrier family 1 member 2 | 0.511 | 0.731 | 0.71 |
|
disease | 0.400 | None | 0.921 | 2 | 0 | 1996 | 2019 | ||||||||
|
glutathione S-transferase pi 1 | 0.383 | 0.923 | 1.4E-02 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.290 | None | 1.000 | 1 | 0 | 2000 | 2017 | ||||||||
|
alsin Rho guanine nucleotide exchange factor ALS2 | 0.647 | 0.423 | 8.7E-12 |
|
disease | 0.200 | None | 1.000 | 3 | 0 | 2001 | 2019 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.200 | None | 1.000 | 1 | 0 | 1999 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.100 | None | 0.918 | 6 | 0 | 2003 | 2018 | ||||||||
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.100 | None | 1.000 | 2 | 0 | 2005 | 2018 | ||||||||
|
neurofilament light | 0.488 | 0.769 |
|
disease | 0.100 | None | 0.968 | 2 | 0 | 1990 | 2020 | |||||||||
|
glutamate ionotropic receptor AMPA type subunit 2 | 0.573 | 0.692 | 1.00 |
|
disease | 0.100 | None | 0.929 | 2 | 0 | 1999 | 2019 | ||||||||
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
disease | 0.100 | None | 0.769 | 1 | 0 | 2004 | 2016 | ||||||||
|
granulin precursor | 0.435 | 0.846 | 7.0E-02 |
|
disease | 0.100 | None | 0.955 | 1 | 0 | 2007 | 2018 | ||||||||
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.100 | None | 0.920 | 1 | 0 | 2000 | 2020 | ||||||||
|
ciliary neurotrophic factor | 0.561 | 0.615 | 2.3E-05 |
|
disease | 0.100 | None | 0.636 | 1 | 0 | 1993 | 2015 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.875 | 1 | 0 | 1999 | 2019 | ||||||||
|
cystatin C | 0.436 | 0.808 | 3.9E-03 |
|
disease | 0.100 | None | 0.818 | 1 | 0 | 2006 | 2018 |