Source: GENOMICS_ENGLAND

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 8626
Gene Symbol: TP63
TP63
tumor protein p63 0.362 0.769 1.00
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.720 strong 1.000 0 0 2006 2017
Entrez Id: 4487
Gene Symbol: MSX1
MSX1
msh homeobox 1 0.525 0.731 0.17
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.700 strong 1.000 1 0 2003 2019
Entrez Id: 5818
Gene Symbol: NECTIN1
NECTIN1
nectin cell adhesion molecule 1 0.523 0.808 6.1E-02
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.640 strong 1.000 1 0 2000 2014
Entrez Id: 652
Gene Symbol: BMP4
BMP4
bone morphogenetic protein 4 0.422 0.808 0.96
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.430 limited 1.000 0 0 2008 2018
Entrez Id: 23133
Gene Symbol: PHF8
PHF8
PHD finger protein 8 0.631 0.577 1.00
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.420 strong 1.000 0 0 2005 2010
Entrez Id: 7020
Gene Symbol: TFAP2A
TFAP2A
transcription factor AP-2 alpha 0.488 0.769 0.99
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.410 strong 1.000 1 0 2000 2015
Entrez Id: 57822
Gene Symbol: GRHL3
GRHL3
grainyhead like transcription factor 3 0.572 0.692 0.99
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.400 strong 0 0
Entrez Id: 50945
Gene Symbol: TBX22
TBX22
T-box transcription factor 22 0.603 0.577 0.98
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.310 strong 1.000 1 0 2011 2013
Entrez Id: 80204
Gene Symbol: FBXO11
FBXO11
F-box protein 11 0.604 0.692 1.00
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.300 moderate 1.000 1 0 2006 2006
Entrez Id: 80004
Gene Symbol: ESRP2
ESRP2
epithelial splicing regulatory protein 2 0.760 0.346 2.3E-07
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.300 moderate 1.000 1 0 2018 2018
Entrez Id: 144100
Gene Symbol: PLEKHA7
PLEKHA7
pleckstrin homology domain containing A7 0.729 0.423 6.2E-09
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.300 moderate 1.000 1 0 2018 2018
Entrez Id: 54477
Gene Symbol: PLEKHA5
PLEKHA5
pleckstrin homology domain containing A5 0.861 0.192 1.00
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.300 None 1.000 1 0 2018 2018
Entrez Id: 7021
Gene Symbol: TFAP2B
TFAP2B
transcription factor AP-2 beta 0.570 0.769 0.99
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.300 None 0 0
Entrez Id: 340419
Gene Symbol: RSPO2
RSPO2
R-spondin 2 0.558 0.577 2.5E-02
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.300 None 0 0